• Research at Analytical DNA Nanotechnology Laboratory (ADNLab) is at the interface of bioanalytical chemistry and DNA nanotechnology. We consider DNA both as important biomarkers for diverse biological processes and clinical diagnostics and also as a class of highly programmable engineering material.

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    New building blocks and simulation tools for DNA nanotechnology

    We aim to enrich the current toolbox of DNA nanotechnology by introducing new experimental and simulation strategies to better manipulate and understand DNA as an emerging class of engineering material.

     

     

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    Three-dimensional DNA nanomachines

    We are also interested in interfacing dynamic DNA nanotechnology with nanomaterials to fabricate and study 3D DNA machines and devices with well-defined function at nanoscale. We explore such devices as superior analytical tools for applications including biosensing, clinical diagnostics, and biocomputing.

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    New detection platforms for point-of-care testing

    Leveraging our expertise in DNA nanotechnology and capability of multi-length-scale engineering, we aim to develop novel diagnostic platforms that are portable, rapid, and inexpensive, with minimal barriers for technology transfer and adoption.